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keratoderma是什么意思，keratoderma翻译
Keratoderma is a medical term used to describe a condition characterized by thickening of the epidermis, or the outermost layer of the skin. This thickening is typically seen as raised, rough, or scaly patches on the skin. Keratoderma can occur on its own as a primary condition, or it can be a manifestation of an underlying disease or disorder.
There are two main types of keratoderma: acquired and hereditary. Acquired keratoderma is caused by various factors such as exposure to certain chemicals, trauma to the skin, or as a result of an underlying medical condition. Hereditary keratoderma, on the other hand, is a genetic disorder that is passed down through generations.
One example of hereditary keratoderma is Palmoplantar Keratoderma (PPK), which is characterized by thickening of the skin on the palms of the hands and soles of the feet. This condition can be inherited in an autosomal dominant manner, meaning that a person only needs to inherit one copy of the mutated gene from either parent to develop the condition.
In addition to PPK, there are other types of hereditary keratoderma that can affect different parts of the body. For example, disseminated superficial actinic keratoderma is a condition that causes thickening of the skin on the limbs, trunk, and face due to prolonged exposure to ultraviolet light.
Keratoderma can also be a feature of other skin diseases, such as psoriasis or atopic dermatitis. In these cases, the underlying condition causes the skin to become inflamed and thickened. Treatment for keratoderma depends on the underlying cause and may include topical medications, phototherapy, or in some cases, surgery to remove the thickened skin.
In conclusion, keratoderma is a condition characterized by thickening of the epidermis. It can be acquired or hereditary, and it can affect different parts of the body depending on the type of keratoderma. Treatment options vary depending on the underlying cause, and it is important for individuals with keratoderma to work closely with a dermatologist to manage their condition.