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ganglioside是什么意思，ganglioside翻译
Ganglioside: A Promising Biomarker for Neurodegenerative Diseases
Gangliosides are a family of complex glycosphingolipids that play critical roles in the structure and function of the nervous system. These molecules are composed of a sphingosine backbone, a sugar moiety, and multiple carbohydrate chains. Found primarily in the brain and peripheral nerves, gangliosides are involved in various neural processes, including cell signaling, neurite outgrowth, and myelination.
Recent studies have shown that gangliosides may serve as promising biomarkers for neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). The levels and types of gangliosides in the brain and cerebrospinal fluid (CSF) have been found to be altered in these conditions, making them potential diagnostic and prognostic indicators.
In Alzheimer's disease, for example, decreases in the levels of certain gangliosides, such as GD1a and GD1b, have been observed in the brain and CSF of patients. These changes are believed to contribute to the neuropathological processes underlying the disease, including neuronal degeneration and synaptic dysfunction. Additionally, gangliosides have been shown to modulate the production of amyloid